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This makes it difficult to select effective siRNA sequences in mammalian genes.
The variety of matching mechanisms makes it difficult to select a proper matching mechanism for a certain context.
That makes it difficult to select cases from before that point without giving unfair attention to certain refugee movements and neglecting others.
The variety of models available makes it difficult to select one that is robust under a wide range of agro-pedoclimatic contexts and effective with limited input data and standard values.
The diversity of state estimation techniques resulting from intrinsic differences in chemical process systems makes it difficult to select the proper technique from a theoretical or practical point of view for design and implementation in specific applications.
Three general defects in the sheet forming process are all observed in the bending process, such as wrinkling instability, over thinning (cracking), cross-section distortion, which makes it difficult to select the optimal forming parameters to solve all the above defects simultaneously due to the interactive effects between wrinkling and other defects.
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Associated minor unconformities have made it difficult to select a defining Global Standard Section and Point (GSSP) for the boundary, which ideally should be located in an uninterrupted stratigraphic section.
Judge Linda G. Baxter of New Jersey Superior Court said that the extensive news media coverage of the first trial of the rabbi, Fred J. Neulander, had made it difficult to select an impartial jury in Camden County.
Due to the variable geotechnical conditions in these areas, which occasionally cause extensive changes between soil layers within a close distance, the stress-deformation field is very complicated and extended, making it difficult to select and design a proper and safe support system.
Starters here are the star of the show, with a choice of 'Spicy Tom Yum Soup', 'Gyoza', 'Tuna Poki Salad' and 'Deep Fried Chiu Yim Squid' making it difficult to select just one dish to kick-start your meal (you'll want it all).
The number of methods for pre-processing and analysis of gene expression data continues to increase, often making it difficult to select the most appropriate approach.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com