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It makes it difficult to screen our clients or to practise safer sex.
This disease is characterized by remarkable genetic heterogeneity, which makes it difficult to screen for pathogenic mutations using Sanger sequencing.
In addition, the presence of many different mutations in Atp7b gene makes it difficult to screen and diagnose WD by genetic testing.
Our analysis revealed that there are several regions with a low degree of polymorphisms between the two parents, which makes it difficult to screen for polymorphic markers in these areas.
However compared to some biotic stresses, abiotic stresses are inherited in a more quantitative manner and may be subjective to assess under field conditions due to confounding environmental factors, which makes it difficult to screen for and quantitate tolerance.
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Some of the characteristics of the disease itself can also make it difficult to screen.
The Food and Drug Administration approved companion diagnostic test (ie, fluorescence in situ hybridization) for identification of ALK-positive patients, however, is complex and has considerable limitations in terms of cost and throughput, making it difficult to screen many patients.
Patients often do not disclose highly stigmatized diseases such as TB and HIV, even when the appropriate questions are asked making it difficult to screen for risks.
Chinese primary care settings have a heavy patient load, shortage of physicians, limited medical resources and low medical literacy, making it difficult to screen for developmental disorders in infants.
Although a mean age of onset of 37 years is reported in the literature, the wide age range for gastric cancer diagnosis is between 16 and 82 years, which makes it difficult to counsel on screening starting age and the more critical PTG age.
The metal band around the phone has hard lips which makes them easier to grip, but the large phone size and curved screen makes it difficult to hold without touching the screen with your palm.
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