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With the full yeast genome in hand, biologists have been able to detect at least 141 different genes that make transcription factors.
Dr. Young showed last year that the genes make transcription factors that act on each other's control sites in ways that in effect form a circuitry for controlling the master regulator genes.
This additional bond can make transcription more efficient and reliable, change the array of RNA binding proteins, or significantly alter the three-dimensional folding of the messenger RNA.
There could be some selection force that keeps coregulated genes in the same region, for example, to make transcription more efficient as a group [ 10].
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Therefore, the intergenic promoter was used to make transcription-fusions with the GUS reporter gene in both orientations and the expression pattern was monitored in detail.
16 Eunmi: Transcription 'eun', making Transcription is making 17 Jiyeon: ((Eunmi reads the text from the worksheet)) 'geulae geuleogo bonikka' ((Melody laughs)) Making RNA 'sseo geunyang.' Right, that's right.
The change in representation required has the effect of making transcription more deterministic - a property we investigate further by stochastic simulation.
This makes transcription factors (TFs) an interesting target for further exploration in this direction [ 6].
The methylation of c-Jun leads to of hyper-condense helix structural change and makes transcription termination which stops OPN mRNA production.
These analyses all give the results that the strand bias profile on both sides of the boundary is similar to the original average shown in Figure 2a, and that when an average over all segments is made, transcription gives a only small modification of the pattern – details not shown.
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