Sentence examples for make this interaction from inspiring English sources

Accessing an extra interaction with the protein via Phe138 gave a significant increase in binding potency compared to similar analogues that do not make this interaction.

However this would involve at least two amino acid substitutions, Ser186→Pro and Glu227→Ala, to make this interaction network similar to that observed in SC18 HA (Figure S1).

We also designed and tested another mutant form of CA04/09 HA involving three mutations to make this interaction network hydrophobic (similar to that in SC18 HA) and showed that this mutant (CA04/09mut2) HA had substantially higher affinity than wild-type HA (Figure S3).

Lack of access to health care could make this interaction difficult, thereby bringing about negative health outcomes.

It has been suggested that the PAM nitrogen could H-bond to the OH of Tyr204 [17] and it is possible that ALN might also make this interaction.

Being both sexually submissive and excessively polite about expressing it makes this interaction completely farcical; you end up with a lot of hideous Hugh Grant-esque dithery mumbling: "Um, could you just, maybe, perhaps, try choking me?

We note that the mismatched combination can also be fixed by making this interaction network hydrophobic.

Apparently, the interaction of the peptide with neutral liposomes is weaker, when compared to the negatively charge membranes, and must be limited to the surface of the bilayer, making this interaction difficult to detect by other methods [21].

Still other chapters dissect and analyze every aspect of the complex relationship between host and agent, successfully making this interaction the central topic.

This makes this interaction a potential therapeutic target for interruption in an effort to stabilize and activate p53 [ 11]. p53 TA adopts an α-helical conformation upon binding to MDM2, MDMX [ 12] or to p300 [ 13].

However, with the F variant, the cysteine at position 223 cannot make this electrostatic interaction and the consequence is likely to be a disruption of the RCL architecture which alters the conformation of the P1-P1' region (the bond cleaved by target NSPs) and may explain the reduced Kass with NE observed here.