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The multi-functional armed structure make this compound an attractive candidate for applications as multi-modified hole transport materials in molecular electronic devices.
The advantages including synthetic accessibility, high potency and selectivity, low toxicity, adjunctive neuroprotective and Aβ aggregation inhibitory activity, make this compound as a new multifunctional lead for Alzheimer's disease drug discovery.
The formation of the photoinduced ICT together with easy and inexpensive preparation make this compound and its derivatives candidate as push-pull building blocks for the design of advanced functional materials.
The specific effects of DITPA on post-infarction SR Ca2+transport and the expression of SR proteins make this compound a potentially useful therapeutic agent for LV systolic and/or diastolic dysfunction.
"make this compound", "check success through crystal structure analysis".
The 40-fold stronger potency of the present lead, combined with its improved selectivity profile in vitro and the availability of a range of analogues, are expected to make this compound a good starting point for the development of a potent and selective agent to study epigenetic regulation in cellular context.
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Representative compound 21 exhibited excellent in vivo pharmacokinetic values at high drug exposure levels in the plasma, which makes this compound promising candidate for a new antitubercular drug.
This status is expected to last in the near future or even improve to the point of making this compound a central participant in the worldwide economic landscape.
The strong dependence of 77KS ionization with pH makes this compound an interesting candidate to be used for the design of pH-sensitive devices.
The ability of ET to cross the blood brain barrier and accumulate in the brain tissues following oral consumption, highlights a possible function in the brain and also makes this compound a viable candidate for studies into neurodegenerative disorders.
Bone accumulation was highest for [68Ga]DOTAZOL, which makes this compound probably an interesting bone targeting agent for a therapeutic approach with 177Lu.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com