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What mechanisms of common regulation make these genes cluster together?
Haploinsufficiency may make these genes particularly susceptible to subtle differences in the genetic background.
Expression patterns and lack of polymorphism make these genes non-classical class II analogues.
The fact that bimodal genes were enriched within the cell membrane and extracellular environment make these genes as candidates for biomarkers for tissue specificity.
Expression patterns and lack of polymorphism make these genes non-classical class II analogues indicating that these molecules may have a unique and yet unidentified function in salmonids.
These features make these genes better candidates for experimental references of transcription and expression levels than currently commonly used housekeeping genes: they can be easily detected, are stable across different tissues and are likely to be HKGs in other species.
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To understand what makes these genes special, scientists may need to run experiments on brain cells.
The increase in As-tolerance and accumulation due to AtPCS1 and CePCS overexpression, observed at the As V) concentrations similar to those found in As-contaminated soils, makes these genes promising candidates for plant engineering for phytoremediation.
Several of these genes were also down-regulated in sigma-infected males, making these genes interesting candidates for controlling the fly's response to viruses.
The combination of their sunlight-induced expression and expected biochemical function makes these genes, listed in Table 1, attractive candidates for involvement in MAA biosynthesis.
Limited recombination makes these genes virtually inaccessible to genetic mapping.
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