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Other limitations possessed by some algorithms that make them unsatisfactory for ChIP-seq data analysis include only finding a single motif or being 'hard-wired' to use a particular type of sequence (e.g. promoters).
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It would house, according to the Abbess, "a kind of sick people, whose desire for God makes them unsatisfactory citizens of an ordinary life, but whose strength or temperament fails them to surrender the world completely".
Rabossi's criteria, which are more restrictive, avoid being too broad, but face the problem of being too narrow, which makes them unsatisfactory.
As an example of what teachers worry about, she pointed to the recent case of a Bronx principal who allegedly made up a "hit list" of teachers she disliked, and then directed her subordinates to come up with reasons to give them unsatisfactory ratings.
Make them secret.
We all make them.
What makes them?
This made them inaccessible.
That makes them ideal".
Some changes can make these unsatisfactory or complete failures.
However, the correlation coefficient method previously used for matching images suffers the drawbacks of being difficult to make calculation and unsatisfactory in accuracy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com