Most of the world's population growth in the next 20 years will occur in countries that make the smallest contribution to greenhouse gases.
From a societal perspective, the economic burden of this disease has been reported in several studies using available data in developed countries; however, the direct medical cost is thought to make the smallest contribution to total costs, accounting for 50% of indirect costs (morbidity and mortality) (3, 4).
Des-HE, in contrast, makes the smallest contribution.
Accordingly, CA XIV is responsible for 55% of all sarcolemmal CA activity and CA IV for 30%; CA IX with 15% makes the smallest contribution.
The criterion "Cost-effectiveness" made the smallest contribution (2%) to the MCDA value estimate.
However, C1 makes the smallest contribution to the overall fluorescence signal due to its shorter lifetime.
Companies appear to be "making the smallest contributions allowed, while taking investment risk in the hope that their gamble will pay off," said Jeremy Gold, an outspoken advocate of duration-matched bonds for pensions funds.
Similar to the results of the SDAI analysis, ESR (as the APR) made the smallest independent contribution to the DAS28 (R2 = 34.0%), and the smallest colinearity (6.6%), although the final contribution was somewhat higher (14.8%).
For a set of synonymous codons, by convention, we define codon 1 as the codon with the lowest inefficiency, that is, the codon which makes the smallest additive contribution to η and is most favored by selection.
Because of the very low degree of control of reaction 5 over its own flux, the direct interaction of ASA with block 5 via reaction 5 makes the second smallest contribution towards the total response despite its relatively high elasticity towards ASA (see Table S1 of Additional file 6).
Indeed, the binding energy derived from the pantetheine arm, combined with the small contribution made by the weak protein surface interactions with the nucleotide, leads to tight CoA binding (Table 2) and, hence, to tight substrate binding.
