Sentence examples for make the extracellular from inspiring English sources

Therefore, the limitations of cytosolic and periplasmic expression of CGTase make the extracellular secretion of CGTases highly needed.

We hypothesize that if we inhibit the aggrecanases gene of chondrocytes, make the extracellular matrix aggrecan of chondrocytes increasing and immunological rejection problems will be relieved.

Having such genes on plasmids make horizontal gene transfer possible coercing the cheaters to make the extracellular products [12].

This could be related to the larger size of the granulomas in the HT host, which would make the extracellular bacilli less accessible to the macrophages due to the higher number of necrotised macrophages.

SPARC can make the extracellular matrix degradation by MMP2 and MMP9.

The ISF, blood plasma and CSF collectively make up the extracellular fluid of the brain and spinal cord.

A Sema domain, a PSI domain (so-called because it is present in plexins, semaphorins and integrins) and four IPT domains (immunoglobulin-like fold shared by plexins and transcription factors) make up the extracellular portion of c-Met.

In order to explain the reduced osteoblast activity and the high bone resorption despite an unchanged number of cells in mutant mice, we reasoned that chondroitin sulfate proteoglycan undersulfation in the bone of dtd mice could lead to altered bone matrix quality, making the bone extracellular matrix more easily degradable by osteoclasts and slowing down matrix synthesis by osteoblasts.

Several attempts have been made using the extracellular domain of Her2/neu (ECD/Her2) as a prophylactic vaccine in mice with no success in tumor prevention.

To study the Neu receptor in vivo, a small deletion mimicking that found in patient tumors [ 10], was made in the extracellular domain, and this construct (termed "Neu deletion mutant (activated receptor)," or Neu-NDL) was expressed by the mouse mammary tumor virus (MMTV) promoter in transgenic mice [ 10, 11].

Here, correction has to be made for the extracellular space and the technique will give overall tissue levels of metabolites, but no information about the concentrations in specific cell types and subcellular compartments.