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These neurons make synaptic contacts with spiny neostriatal projection neurons.
Tomassy said it is possible that these profiles of myelination "may be giving neurons an opportunity to branch out and 'talk' to neighboring neurons". For example, because axons cannot make synaptic contacts when they are myelinated, one possibility is that these long myelin gaps may be needed to increase neuronal communication and synchronize responses across different neurons.
As indicated in Fig. 4a, immature photoreceptors (both cones and rods) initially make synaptic contacts with the output layer of the developing retina at the inner plexiform layer (Johnson et al. 1999).
Native fibers make synaptic contacts with nearly all ganglion cells within one month of cervical trunk section; within 6 months the degree of innervation, judged by measurement of excitatory postsynaptic potential (e.p.s.p). amplitude and electron microscopical synapse counts, approaches normal.
Upon arrival, DA fibers make synaptic contacts throughout the LGE and cortex, with axonal branching, pruning and synaptogenesis continuing into the first weeks of postnatal development.
This anatomy resembles that of hair cells, the force-sensitive epithelial cells of the inner ear that make synaptic contacts with afferent terminals.
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Ultrastructural investigation demonstrated that vesiculated efferent nerve endings make synaptic contact with the outer hair cells in the organ of Corti and with type II hair cells in the vestibular end-organs.
Besides growth factor effects on functional maturation it is likely that precursor cells are driven towards differentiation by the neurons that make synaptic contact with them.
These include thin unmyelinated C-fibers and myelinated Aδ-fibers, whose central terminals make synaptic contact with second order neurons that are at the origin of pain-related pathways [25].
The integration of glomeruli expressing different receptors occurs within each subdomain only and no study has reported, to our knowledge, evidence that any AOB neuron -projection or interneuron- would make synaptic contact with terminals from both subpopulations.
Because A-type horizontal cells make synaptic contact exclusively with cones, these observations indicate that the circadian clock in the mammalian retina substantially increases rod input to A-type horizontal cells at night by enhancing rod-cone coupling.
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