Sentence examples for make such trials from inspiring English sources

International collaboration is essential as is a close partnership between academia and industry to make such trials feasible.

For example, several randomised controlled trials have included expected survival time in their eligibility criteria, and a nomogram that can more accurately predict survival can provide valuable information for this consideration, potentially making such trials more sophisticated (Iasonos et al, 2008).

The vast differences and bias in the randomized trials using surgical procedures of site-specific cancers, as well as the biological, pharmacological and intrinsic activities of experimental drugs generated in the body would make such crossover trials senseless, if not harmful for the patients [7 9, (Khatami, manuscript in preparation)].

It has been previously estimated that a population base of around 67 million would be required to conduct a 5-year trial of this nature, 33 so such a trial would be a major undertaking, although the effect sizes noted in our observational study and adaptive or 3-arm trial designs may make such a trial more feasible.

Nevertheless, the limited number of patients for such a trial and the promising results of stenting make such a trial difficult if not impossible to perform.

The differences in the setup and specification of the intervention of the relevant trials make such an approach prone to additional bias and therefore difficult to assess the benefits and harms of the intervention.

Although data for this study are not yet mature, these differences in clinical trial design make such studies in adjuvant chemotherapy for patients with high-risk prostate cancer novel and promising.

Despite these difficulties, the potential benefits to be gained by conducting a properly powered trial would make such a demanding exercise worthwhile.

When planning investigations of clinical heterogeneity in systematic reviews of controlled trials one should make such plans explicit, a priori, in the protocol for the review.

But the idiosyncrasies of the trial process generally make such judgments unwise.

Ethnic groups or nations must comprise at least 20% of the trial population to make such analyses feasible [ 40].