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She wanted to make significant change in the state.
The people and the strategic elements exist for him to choose a path to victory in 2012 that will position him and the Democratic Party to make significant change in his second term.
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President-elect Barack Obama and Mr. Daschle have signaled a desire to make significant changes in health care, but absent changing how care is delivered, investments will be inefficient, and the public won't get the quality of care we are capable of.
But changing the system required the notoriously bureaucratic Army to make significant changes in the way medical helicopters were positioned, as well as increasing coordination between hospitals, forward surgical teams and front-line units.
VITAC has to make significant changes in technique before court reporters can go on the air as captioners.
Most of the troublesome referendums appropriate money, cut taxes or make significant changes in spending or collection.
Executives involved in negotiations with the European officials say that AOL and Time Warner may have to make significant changes in the deal to buy EMI.
But Mr. Sharon criticizes the plan as undercutting Israel's security, and he plans to lobby Mr. Bush to make significant changes in it.
Health insurers said today that Congress needed to make significant changes in the overall legislation to maximize the number of private health plans that would enroll Medicare beneficiaries.
Both coaches and mentors can be the support and accountability partners you need to make significant changes in your working life.
Eventually, he turned to me and summed up with a groaner: "We firmly believe — no pun intended — that a mattress can make significant changes in sleep quality".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com