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A more serious worry confronts IP when you have to make sequences of decisions.
With the high background level of polymorphism, postmortem changes in the DNA can make sequences from long-dead animals hard to align with those of freshly sampled ones.
Recombination is known to have a strong influence on molecular clock analyses [46], [47] and can make sequences appear as though they are evolving either more rapidly or slowly than they are in reality.
Resources are needed to develop and sustain the bioinformatics infrastructure and to make sequences available to genomics reference banks so that EIPs can play a broader role in advancing public health practice.
Similar(55)
Many proteins interact in the space of the major groove, where they make sequence-specific contacts with the bases.
Continued advances in DNA sequencing technology will make sequencing a routine biological assay.
Therefore, tenOever and his colleagues had to figure out how to make sequence modifications that still produced functional viral proteins.
Apart from specific domains, the low sequence identity between WS/DGAT and other CoA-dependent acyltransferases family make sequence comparison a good approach to differentiate them.
These significant differences make sequence alignments of Rieske proteins controversial, compared to their ribosomal RNA alignments.
MSARI utilizes RNAFOLD 40 to generate RNA secondary structure in multiple sequence alignments and CLUSTALW 41 to make sequence alignments.
Such vast amounts of repetitive DNA hinder the efficient large scale sequencing and also make sequence analysis much more complicated and time-consuming.
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