A major strength of the current study is the large sample size which has allowed us to generate stable estimates and make robust comparisons.
Some of the case scenarios in this study were modified from the study by Balkau et al. [ 3]; we can therefore make robust comparisons between physicians in Taiwan and physicians in European countries.
Although this approach allows us to make robust comparisons with evidence reported from England and elsewhere, it may obscure the finer detail of symptom patterns and clusters as they evolve over time, and their effects on timely help-seeking by patients and timely diagnosis in primary and secondary care.
In 2001 the devolved government ditched school league tables; it has also replaced some standardised tests with teacher assessments, making robust comparison of schools impossible.
As the number and range of scenarios assessed has grown, so has the range of estimated values, especially for analyses considering different management regimes (see, e.g., [59]), making robust cross-comparison more challenging.
In order to make the robust comparisons, in Fig. 8, actual peak demand data has been multiplied by a scale of 2. The depiction of the graphs in Fig. 8 suggests that in 2011, peak demand declined faster and likewise increased faster in 2012 and for nonpeak demand on the other hand in 2011, declined mildly and as well increased mildly in 2012, leading to some sort of catch-up by peak demand.
After consulting with expert statistical colleagues, we concluded that there were insufficient numbers in each VNTR-defined outcome group to make statistically robust comparisons based on multiple comparisons of exposure to ward environments or among patients.
Due to the trapping regimes employed, we were unable to obtain comparable number of samples from the 11 sites, making robust among-site comparisons unattainable.
There are now calls for a RCT to make a robust comparison between the above treatment modalities.
There were very few Black women in the higher socio-economic categories, which made a robust comparison difficult.
16, 17 Many prospective and retrospective studies on rasburicase assumed superiority over allopurinol; therefore, comparator groups, where present were, for the most part, different doses or durations of administration of rasburicase, which makes a robust comparison of rasburicase with allopurinol in the reduction of LTLS/CTLS and need for RRT difficult.
