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We even went as far as to create a public webpage where anybody can review and rate the same abstracts as we did to make replication as easy as possible.
In March Dr Nosek unveiled the Centre for Open Science, a new independent laboratory, endowed with $5.3m from the Arnold Foundation, which aims to make replication respectable.
Too often, rules are so vague and complex as to make replication impossible".Fibonacci numbers at least have the virtue of creating a testable proposition; one that they appear to fail.
Often, only people with an axe to grind pursue replications with vigour a state of affairs which makes people wary of having their work replicated.There are ways, too, to make replication difficult.
A situation that may make replication even more difficult is long-range LD or cross-chromosome LD which may exist in the human genome [18].
It seems more likely that single motif gM mutants have subtle defects that are important for evolutionary fitness, where a 10% difference in virus transmissibility would have a major impact, but hard to detect in experimental pathogenesis, where transmission is hard to reproduce and limits on animal numbers make replication reductions of <90% hard to demonstrate.
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The replicating chains were caught in oily bubbles, which protected them and made replication easier; eventually, they began to venture out into the open sea.
The recommendation is to check for interaction with other polymorphisms (see, for example the replicability of 'novelty seeking', where interaction of at least three gene loci made replication uncertain [ 122].
"Video makes replication more efficient," Pritsker said.
Mr. Steeg said a one-and-a-half-inch hologram had been set on every Super Bowl ticket, making replication virtually impossible.
Thus if a replication fails, it could be because the repeaters didn't quite get these je-ne-sais-quoi bits of the protocol right.Taken to extremes, this leads to what Dr Collins calls "the experimenter's regress"—you can say an experiment has truly been replicated only if the replication gets the same result as the original, a conclusion which makes replication pointless.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com