Sentence examples for make randomised trials from inspiring English sources

Some advocates of the vaccine argue that logistical difficulties, great expense, and ethical concerns make randomised trials unsuitable for resolving the pneumococcal vaccine controversy [ 34].

Some of these factors make randomised trials unfeasible in educational settings, thus necessitating other designs such as non-randomised controlled and before and after studies.

We however note that an important consideration in developing the IGCC classification was that all the prognostic groups should be large enough to make randomised trials of new treatments for each prognostic group feasible (IGCCCG, 1997).

North America has also produced some such trials, but the system over there makes randomised studies hard to conduct.

The relatively low number of women eligible to be recruited in each country made a randomised trial design comparing MRI screening to no intervention or to conventional breast imaging unfeasible.

High patient losses also make interpretation of randomised trials difficult.

Extubation decisions can potentially be made based on randomised trials and not on observational studies alone.

They might be called the "peace corps" of economists, bringing the blessing of their investigative technique to the neglected villages of India or the denuded farms of western Kenya.Ms Duflo has made her name carrying out randomised trials of development projects, such as fertiliser subsidies and school recruitment.

When subsequent randomised trials made it painfully clear that the intensive care unit (ICU) patient outcomes did not match up to expectation [ 7, 8], the concept was generally discarded, even from the surgical patient population in whom the benefit was repeatedly seen [ 9, 10].

Estimating proportions and likelihoods for each of these groups may make assumptions that hold better in randomised trials and less so in the observational setting.

Earlier MRC guidance for evaluating complex interventions focused on randomised trials, making no mention of process evaluation. 2 Updated guidance recognised the value of process evaluation within trials, stating that it "can be used to assess fidelity and quality of implementation, clarify causal mechanisms and identify contextual factors associated with variation in outcomes".