In conclusion, we demonstrate that an advanced mammalian regulatory network model based on experimentally validated cis-regulatory interactions has allowed us to make novel, experimentally testable hypotheses about transcriptional mechanisms that control differentiation of mammalian stem cells.
Think about it: What makes novels such as "Huckleberry Finn" or "Gravity's Rainbow" compelling are not their generalities but their specificity -- the tracing of particular events and interactions, the development of Huck or Jim or Tyrone Slothrop as characters, not archetypes.
We searched our results for novel interactions that were made with members of this family, which did not exist in the DIP database.
Because compound 2 is a high-potency hDAAO inhibitor (Ki=7 nM) which lacks both of these two features, the novel interactions of compound 2 with hDAAO are presumably strong enough to make up for loss of these two interactions.
But it is inspiring novel interactions between government, industry and academia to find solutions to the continent's challenges.
To find novel interactions we used two different methods.
Those novel interactions represent putative interactions which are not yet experimentally proven.
We found a large proportion of our interaction set to comprise novel interactions.
In addition, we uncovered several novel interactions.
However, research has also shown that people threatened with social exclusion express greater interest in making new friends, and retain more positive first impressions of novel interaction partners, than do those not threatened with social exclusion [34].
