The homeodomain makes major groove contact, via helix turn helix motif, and minor groove contacts, via the N-terminal arm of the homeodomain with DNA [ 9].
Make major changes if necessary.
But still, it makes me nervous that I would have to contact them after I started making major changes to my machine".
The β-Gal of the precursor makes a major contact with the "bottom" of the binding interface, which is stabilized by residue T397, while the Le epitope, the α-1,3/4 Fuc (Le Fuc), contacts with another part of the "bottom" and is stabilized by the other "wall" (S346′, T347′, G348′ and D349′) to support the binding outcomes (Figs. 5D, 6 and 7D).
No French units, as yet, had made any major contact with the Viet Minh.
Three amino acids make the major nucleotide contacts and adjacent residues may contribute additional contacts and influence the positioning of the major nucleotide contacts.
They did not improve his reflexes, his vision, his timing, his ability to make clean contact with major league pitches, which is how he hit all those homers.
"He looked at me, I looked at him," said one witness, Sgt. Alonzo M. Lunsford Jr., as he described how he and Major Hasan made eye contact when the major trained a laser-guided handgun on soldiers in a processing center on base.
We were able to identify a conserved domain in the N-terminal regions of all tyrosine recombinases, which is comprised of three core α-helices that usually make a contact with the major groove of DNA.
Many proteins interact in the space of the major groove, where they make sequence-specific contacts with the bases.
