In addition, Tat's exceedingly strong affinity for other proteins and glass/plastic, and its temperature susceptibility, make it impossible to determine exactly what fraction of the Tat "starting dose" actually reaches the experimental specimen, thus likely leading to an underestimation of Tat functions in vitro [39].
In addition, Tat's exceedingly strong affinity for other proteins and glass/plastic, and its temperature susceptibility, make it impossible to determine exactly what fraction of the Tat "starting dose" actually reaches the experimental specimen, thus likely leading to underestimation of Tat functions in vitro [61].
For example, the FBI-police pact would make it impossible to determine whether local law enforcement were properly trained to operate the surveillance devices.
But Mr. Card's critics, who include Democratic elected officials in Nevada and South Carolina who are at odds with some of his decisions, say his ties to the industry make it impossible to determine whether his favorite projects are good public policy or favors to old colleagues.
The United States Preventive Services Task Force, a federally sponsored panel of experts in primary care and prevention, reports that there are no studies establishing the effectiveness of screening and that the uncertainty of the benefit and the known risks of early treatment make it impossible to determine whether there is any advantage in screening the general population.
His outlandish and often incompatible claims, along with his refusal to admit mistakes, make it impossible to determine which of his notions are likely to become policies, and can foster the sinister impression that, as President, Trump will be accountable to no one, not even himself.
The estimation of the incidence is complicated by the occurrence of hypoglycemia unawareness, which by its very nature makes it impossible to determine true incidence.
This study is limited by its cross-sectional design, which makes it impossible to determine the directionality of associations.
The major limitation of our study is its cross-sectional design, which makes it impossible to determine the temporal ordering of the association between arterial stiffness and increased levels of inflammatory-related serum proteins.
Another important limitation of this study is its cross-sectional design, which makes it impossible to determine the direction of the causal relationship of harmful alcohol use with periodontal status.
This makes it impossible to determine the boundaries of the law.
