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Exact(42)
Differences in the loops that form the walls of the substrate binding groove in Spy0129 make it difficult to predict its likely binding determinants from comparison with SrtA.
The fresh nuances of Chambers Bay make it difficult to predict whether Kaymer will prevail again.
Deflation depresses investment by corporations because falling prices make it difficult to predict returns and make debts harder to pay off.
At least some of the losses stemmed from profit taking, said Brian G. Belski, market strategist for Piper Jaffray & Company, but the emotions of earnings season make it difficult to predict trends.
They are the ones when so much goes wrong for them and they make it difficult to predict with any certainty that they can end a 12-year wait for the Premier League title.
A ski patroller explains that most of Niseko's slopes are angled in the 35‑45 degree range, which is what everyone wants – but that wind and snowpack make it difficult to predict where avalanches will occur.
Similar(15)
The comprehensive nature of this technical shift makes it difficult to predict its impacts.
However, some results in it have been derived under simplifying assumptions, and the complexity of a deployable MH MIMO system makes it difficult to predict its realistic performance.
Despite its large size, outside of the DSPc domain, there are no recognizable protein domains in dusp27, making it difficult to predict its mode of action.
USC's offensive game plan changed dramatically in its first two games, making it difficult to predict what Coach Steve Sarkisian intends to do Saturday at Boston College.
Political squabbling has made it difficult to predict where the theater will end up.
More suggestions(15)
making it difficult to predict
make it difficult to maintain
make it impossible to predict
make it difficult to develop
make it difficult to provide
make it difficult to work
make it difficult to implement
make it difficult to create
make it difficult to establish
make it difficult to remove
make it difficult to understand
make it difficult to change
make it difficult to follow
make it difficult to measure
make it difficult to anticipate
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