Mr. Madoff's intricate and overlapping ties with the American Jewish community and its organizations make it difficult to assess the damage precisely.
The intelligence report's lack of even hints at the kind of evidence collected make it difficult to assess the claims, and its weakness gave Russian officials ample opportunity to poke fun.
The significant difference in prevalence estimates of childhood obesity produced by the three growth references make it difficult; to assess the extent of the problem and its associated health burden, to conduct research, to make population comparisons and to inform policy.
The limitations the Israelis have imposed on foreign journalists make it difficult to assess the situation.
However, dynamic changes in mRNA folding throughout translation make it difficult to assess translation efficiency.
Those fluctuations, combined with the sheer range of plants that stinkbugs eat, make it difficult to assess their economic impact.
But the government's extraordinary security measures may prevent any large gathering and make it difficult to assess the true depth of Ms. Bhutto's following.
The complexity of the evidence that led to Wilde's conviction in 1895 for gross indecency – including evidence of procuring male prostitutes – would make it difficult to assess.
Differences make it difficult to assess governance conditions in a comparative sense, and call for a framework to think about this issue.
This can make it difficult to assess the feasibility of reintroduction when an extirpated species cannot, by definition, be observed in the landscape of interest.
