Sentence examples similar to make it difficult to alter from inspiring English sources

Rampant infighting also made it difficult to alter strategy, since any changes — like pouring more money and staff into the Iowa caucuses later won by Obama, or emphasizing her character, as some aides favored — meant surrendering turf.

As excess Fe is toxic to cells, plants have developed sophisticated mechanisms to control Fe flow, making it difficult to alter Fe transport.

As bridge-slab thickness increases, both structural stiffness and dead weight increase, which makes it difficult to alter the natural vibration frequency.

On the other hand, the tight packing structure of Hox genes makes it difficult to alter the expression profiles of these genes and to explain how each gene is influenced differently by a common regulator.

(R10) Peer influence ('sangat') makes it difficult to change behavior.

We have shown how dietary influences and altered urinary NOx clearances make it difficult to interpret serum and urine NOx levels.

Skin conditions like acne, eczema and rosacea can alter your skin's appearance and make it difficult to determine skin tone.

These properties make it difficult to detect.

Also, inconsistent methodologies make it difficult to compare study results.

Such views make it difficult to quit using these substances.

However, methodological shortcomings make it difficult to compare studies.