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The development and validation of such a method that is able to characterize molecule synthetic accessibility as a score between 1 (easy to make) and 10 (very difficult to make) is described in this article.
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The work conducted so far is reported and the progress made is described.
The Discovery Bus, a multi-agent software system designed for automating aspects of Molecular Design, particularly expert decision making, is described.
Every move he makes is described by the narrator.
The adaptations of the indicators were characterized and the farmers' explanations for the changes made were described.
The types of genetic manipulations that can be made are described, along with proposed mechanisms for both double-stranded DNA- and oligonucleotide-mediated recombineering events.
The significance tests made are described in the Supplementary Material.
A great deal of effort was put into interviewing all patients within these time frames; exceptions that had to be made are described in the results section.
Decision making was described as particularly difficult for relatives when the patient's wish was unknown and/or if relatives disagreed with each other about the decision.
Changes made were described and summary measures (mean and median) before and after discussion compared using paired t test and Wilcoxon Signed Rank Test.
The number and type (touch, talk) of contacts made was described across the whole dataset, for each category of location and for each participant.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com