High electron density and homogeneous shape and size make GNPs highly conspicuous in TEM images.
The resulting thiolated HRCA products were then captured onto GNP surface and made GNP more salt-tolerant.
Moreover, the decrease in size may lead to an exponential increase in surface area relative to volume, thus making GNPs surface more reactive on itself (aggregation) and to its surrounding environment (biological components).
Moreover, decreasing size may lead to an exponential increase in surface area relative to volume, thus making GNPs surface more reactive on aggregation and to its surrounding biological components.
The results of this study indicate that decrease in GNPs size produces an exponential increase in surface area relative to volume, which may make the GNPs more self-reactive (i.e., may promote aggregation) and more prone to interactions with surrounding molecules (biological components).
The current study is based on the hypothesis that the reduction in size per se may make harmless GNPs toxic to live animals.
Silica nanorod was chosen as a matrix to make the GNP-SiNR hybrid.
When relatively lower molar ratio of PS 1 (2 or 4) made stable GNPs conjugate, however, higher molar ratio allowed unstable GNPs conjugate and remains continuous aggregation [ 35].
Moreover, the orientation relationship between the aligned GNPs towards the extrusion direction and the matrix grains with a fiber type texture makes the GNPs and [0001]Mg precipitate rods constitute a hybrid strengthening architecture in the composite.
Hence, cyclic RGD conjugation makes the GNP-based radiosensitizer tumor targeting, offering a new modality for enhancing radiotherapeutic efficacy.
Furthermore, because this simplified method involves fewer steps compared to the procedure used by Chen and Wen [26], it is a highly reproducible method for making spherical GNPs of consistent quality.
