Sentence examples for make functional inferences from inspiring English sources

Regarding gene regulation, having worked on the Wellcome Trust Genome Campus for the past two and a half years, I've absorbed approaches that harness human genetic variation and comparative genomics to make functional inferences.

Information from basal lineages is necessary to better describe that diversity, to polarize the changes that occurred during angiosperm evolution, and to make functional inferences about the common ancestor of early angiosperms.

Conservation of a gene in an operon is thus a strong indication of functional neighborhood and can be used to make functional inferences (Overbeek et al. 1999; Moreno-Hagelsieb and Janga 2008).

In addition, the use of different sources of information out of BLASTP and FASTA searches allowed to make functional inferences for proteins with no clear functional assignment based only on sequence similarity searches.

Similarly, an example of VLDS with large number of variables as well as units of analysis is an functional magnetic resonance imaging study of neural changes underlying speech-perception training [ 2] in which whole brain images of 40 patients were taken to make functional inference, resulting in hundreds of time series data clustered within thousands of voxels.

In the second task, MRF-Deng makes functional inferences by Gibbs sampling across all unannotated proteins, as described above.

We clustered 1,729 proteins by their functional associations and made functional inferences from detailed analysis on one subcluster highly enriched in the TGF-β signaling pathway (P<10−50).

This result is reasonable because our algorithms identified significant protein pairs that are more functionally associated than the direct-interacting pairs in the human PPI data, and we made functional inferences from these significant pairs, not from direct protein interactions which may suffer large amounts of false positives generated in high throughput assays.

Though primers were designed based on the apparent sistergroup relationship of Microcebus and Otolemur V1R sequences to Mus subfamily G, a more focused analysis reveals uncertainty in the relationship of the V1R strep clade to the V1R subfamilies identified in Mus (supplementary fig. S1, Supplementary Material online), thus making functional inferences tenuous at best.

We made this distinction as most of the sequences of the test set share over 70% sequence identity with first BLAST hits and this could positively affect the assessment making functional inference an easy task.

Particularly informative are the clusters of 'flexible genes' collected in genomic islands (GIs), which contain groups of contiguous genes, making functional inference much more reliable.