Sentence examples for make favorable interactions from inspiring English sources
Design of NNRTIs that make favorable interactions with the Asn103 side-chain should be relatively effective against the Lys103Asn drug-resistant mutant.
(b) Structural alignment of uncleaved GP to the EBOV GPCL ADI-15946 complex shows that the mAb miGPCL ADI-15946able interacomplexwith the glycan cap even though binding dishowses thatglycan cap β17-β18 loop from the 310 pocket (arrow showing displacemAbt of loop).
Large-scale computational screening, employing the program DOCK, was used to perform atomic-level docking of 1.4 million small molecules to prioritize those making favorable interactions with the BoNT/E site.
Thus all the three analogues of quinazolines makes favorable interactions inside the active site of the human gamma-aminobutyric acid receptor and they are possible ligands of it.
The crystal structure of the phosphorylated peptide bound to BCL-XL revealed that the phospho-Ser158 makes favorable interactions with two BCL-XL residues, which cannot be formed with unphosphorylated Ser158.
The preference of some Prxs for organic peroxides has been attributed to a "hydrophobic collar" of apolar side chains around their active site that can make favorable hydrophobic interactions with the hydrocarbon part of the substrate.
By way of example, sidechains that carry a negative charge would be positioned to make favorable electrostatic interactions with a cluster of positively-charged residues located in the RNAP secondary channel (the 'basic rim'; Vassylyev et al., 2007b; Zhang and Landick, 2009).
The decreased activity of VA-1 is most likely explained in terms of interference with sugar-mediated dimerization whereby the acrylamide makes it sterically more difficult to form favorable interactions.
(c) The heavy and light chain of ADI-15946 may form favorable interactions with the glycan cap.
Hence, although TDG makes favorable protein interactions to e.g. Phe 27 at this passage, there is significant steric resistance.
The presence of hydrophobe (H) is also consistent with the docking results, and the presence of side chains of many amino acids like ASP253, PHE256, and SER251 makes favorable hydrophobic interactions.
