Sentence examples for make favorable contacts from inspiring English sources

The energy of the protein decreases as its residues make favorable contacts.

Several residues make favorable contacts general to all amino acyl groups, while others may play a greater role in enforcing glycine selectivity.

We suggest that t1-nucleotide analogs that make favorable contacts inside the t1-binding pocket could lead to anti-miRs that specifically target the Argonaute-miRNA complex.

As both ligand classes (2 4 and 6 and 7) most likely make favorable contacts with different conformations of the αC helix, this structural element appears to be unique in Fyn1.

In silico docking simulations revealed that 13a, via the p-chlorobenzyl and pentafluorobenzene groups, made favorable contacts with the two adjacent amphipathic pockets.

While the added methyl group in Leu-550 introduces steric clash with the imidazo[1,2- b]pyridazine scaffold of ponatinib, Leu-550 is still able to make favorable hydrophobic contacts with the dimethoxyphenyl ring of FIIN-2.

Thus, surfaces coated with PEG, or betaines, resist adventitious protein adsorption because (i) there are no charges to make favorable electrostatic contacts with proteins, and (ii) the hydration shell effectively looks like water to the proteins, and so there is little driving force for protein surface binding.

The first group consists of solvent-exposed residues which likely make energetically favorable contacts with the antigen and thus comprise the functional-binding epitope.

Such residues at positions outside of the usual pockets are able to make energetically favorable contacts because of their large size.

These data indicated that the NPF motif and flanking residues were able to make more favorable contacts with EHD1-EH within the context of a cyclic scaffold.

The structures demonstrated that the inhibitors bind preferentially at the catalytic site and promote the less active T state conformation of the enzyme by making several favorable contacts with residues of the 280s loop.