Exact(7)
Radiation effects are especially significant for polar flights, because the cosmic radiation particle flux increases with increasing latitude and altitude, being significantly higher on board aircraft than at ground level; however, the complexity of the radiation field does not make dose measurements easy.
Physicians may have used guidelines other than the one we used in the study to make dose adjustments.
On the other hand, the hepatic route of elimination for linagliptin may make dose adjustment necessary in patients with hepatic failure.
The clinical pharmacist did not make dose titrations for antihypertensive medications, instead recommendations were made in the medical record and the primary provider was alerted.
For example, this deviation seen in neonates would be of more clinical relevancy if the model is intended to be used to make dose recommendations than to suggest sampling times.
Furthermore, monitoring of replacement therapy to optimise the individual replacement dose or make dose adjustments is largely based on clinical signs and symptoms, rather than objective biological serum markers assessing the tissue activity of cortisol.
Similar(53)
It is a major requirement to make dose-dense therapies feasible.
Levetiracetam has a wide therapeutic window and predictable pharmacokinetics which make dosing convenient.
In in vivo experiments, these agents were suspended in 0.5 w/v% methylcellulose 400cP solution (Wako Pure Chemical Industries, Osaka, Osaka, Japan) to make dosing formulations.
"We considered making Dose more mission-driven," he said.
Included in making dose assessments for the three CoP are calibration coefficients for a range of beam quality indices.
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