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The AIDS experience has demonstrated that poor countries can make complex treatments accessible to many people.
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This would place equal value on the art of "not doing"—making complex decisions not to give treatments, not to order tests, and to stop current treatments when in the best interests of the patient.
Patients with pharmacoresistant temporal lobe epilepsy (TLE) contemplating brain surgery must make a complex treatment decision involving trade-offs.
Alongside these changes in practice, health professionals have an obligation to ensure patients can make informed decisions about the complex treatment choices being presented to them.
As these children progress through paediatric services and into adult care, their life-long exposure to HIV and complex treatment histories make them a different population from their age-matched young adult counterparts.
Virtual MDT clinics have been developed in adult HIV practice across the UK and USA for over a decade to support complex treatment decision making.
Combined multidisciplinary virtual input with adult expertise in resistance and newer agents, paediatric knowledge of pill swallowing, childhood formulations/weight banding and parental support, assists complex treatment decision making in paediatric HIV infection.
The complex, systemic nature of the disease makes RA treatment complex and involving a variety of approaches.
"If what I think is an ideal result would make the treatment more complex and in my eyes this should be a high priority, if in the patient's eyes it isn't, I have to deal with that.
Various aspects of therapy, such as drug interactions, overlapping toxicity and the risk of immune reconstitution inflammatory syndrome (IRIS), make the treatment of TB complex in HIV-infected persons.
This is particularly relevant for advanced cancer patients who are often overwhelmed with difficult decisions to make, through complex information and available treatment options, and are frequently co-managed by the breast cancer and the palliative care teams.
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