Many prognostic signatures are published but inadequate validation makes clinical use futile [ 34].
The knee program alleviates the use of tissue aids and makes clinical use much simpler; however, it is currently only available for use in clinical research and its precision for periprosthetic BMD measurement in the tibia has not been evaluated.
Master physicians already make clinical decisions using personalized algorithms, which were learned early in their careers and then refined through clinical experience and lifelong learning.
This would make clinical sense since using these more potent opioid type drugs in the elderly has been associated with increased rates of falls and bone fractures [ 21].
Although our results appear to be robust, they cannot be used to make clinical predictions.
Erlotinib levels were not used to make clinical decisions.
It is absolutely essential that, before a marker be ordered or used to make clinical decisions, analytical validity is established.
In this case, other information, such as family history, is used to make clinical management decisions [ 11, 27, 28].
This indicates the need to proceed cautiously when making clinical decisions using such sensors, and suggests that users should focus on the three strongly correlated parameters for further analysis, at least in the older population.
