Sentence examples for make clinical development from inspiring English sources

This would thereby make clinical development of this class of compounds more cost effective by inhibiting racemization which can occur over long periods of time at room/elevated temperature.

Genomic alterations such as point mutations and copy number variations, epigenetic changes such as methylation and histone modifications, as well as gene expression changes have been previously revealed in oral squamous cell carcinoma (OSCC), which could facilitate biomarker development and make clinical decisions [ 3].

Whilst this open-source component-based approach has undoubtedly made clinical software development easier, clinical software projects are still hampered by problems that traditionally accompany the software process.

Most patients are still diagnosed at an advanced stage, making clinical strategy development for diagnosing pancreatic cancer at earlier stages essential.

While awaiting these promising developments, clinicians should be cautious when making clinical decisions based on individual values of the SpHb.

Most existing predictive models for asthma development in children make predictions at a time unsuitable for making clinical impact.

This has led to investment of time and resources by industry, regulatory authorities, governments, and nonprofit organizations to develop the infrastructure needed to make the advanced clinical development of RSV vaccine candidates a reality.

Good progress has been made with the clinical development of new TB vaccine candidates with twelve being actively tested in clinical trials.

To date, HDAC6 selective inhibitors (tubacin, tubastatin A) have only contributed to validate HDAC6 as a target, but their unfavourable pharmacokinetic (PK) profiles have prevented them from further pre-clinical and clinical development, making them only good research tools (Haggarty et al, 2003; Butler et al, 2010).

Based on the observation that over the last 30 years the cost of development has risen regularly as the number of new chemical entities reaching the market has fallen, how can "savings" be made in terms of clinical development, the objective being more rapid access to a drug for medical needs that are not covered?

"By investing in translational medicine, including better neuroimaging and biomarker strategies, we will be able to make better decisions earlier in clinical development and improve the productivity of our R&D efforts".