Sentence examples for make binding predictions from inspiring English sources
This should be expected considering that sequence-based methods generally rely on far more input parameters than structure-based methods in order make binding predictions and also are directly fit to experimental binding data for a similar or identical MHC allotype.
ProbTF [ 76] method is used to make TF binding predictions on promoters of all RefSeq genes.
We developed a webserver with an intuitive visualization scheme for summarizing the T cell-based antigenic potential of any given protein or proteome using human leukocyte antigen binding predictions and made a web-accessible software implementation freely available at http://met-hilab.cbs.dtu.dk/blockcons/.
Feature values may depend on the TF t, as is the case for motif scanning, or on the cellular condition for which TF binding predictions are being made (as is the case for HAc-derived features).
This degeneracy of functional AREs, and also the divergence from the in vitro-derived binding sequence, make computational prediction of AR-binding sites in the human genome problematic.
Two distinct characteristics make the MHC-II peptide binding prediction problem very difficult.
35, 62, 63 In IEDB, the binding prediction is made from four PSSM-based models for Class I HLAs, while for Class II HLAs, the result comes from nine models including several PSSM-based models and machine learning models.
We demonstrate that the agent-based spatial model can effectively address problems associated with combinational complexity and make testable predictions about adaptor binding and signaling output that are consistent with novel, quantitative experimental data sets.
TF binding prediction, in turn, makes use of given DNA-binding specificities to predict putative TF binding sites.
Once the model is trained, SimBoost can make predictions of the binding affinities for unobserved drug target pairs, based on their known features.
To make a prediction for binding affinity, we use the median of the interval.
