However, there has been a lack of follow-up studies of the impacts of the quota system on the economic or social aspects of New Zealand fisheries, making assessment problematic.
Unfortunately, available characterization data vary widely in accuracy, precision, and granularity, making assessments problematic.
Regression of the tumour as multiple, scattered tumour deposits may also make assessment of the longest diameter problematic, with different approaches to measurement that either include (Rosen et al, 2003; Wright et al, 2010) or exclude (Cheung et al, 2003; Bollet et al, 2007) intervening normal tissue.
This has been absent from many exercise intervention trials, making assessment of benefits problematic.
That disruption, plus the airy openness of the outdoor venue, dissipated intended dramatic tensions of the work and made its assessment problematic.
Heterogeneity between trials, in terms of interventions and outcome assessment, also made assessment of some outcomes problematic.
Both manual and automated annotations vary in quality between databases and annotators, making assessment of annotation reliability problematic for users.
Identifying the positive impact of mobiles can be difficult because they have so many uses, making assessment of costs and benefits problematic.
In addition, the fluorescence assays used are technically difficult in shoot tissues due to the higher autofluorescence, making assessment of possible induction of autophagy in shoot cells problematic.
Moreover, high inter-observer and sampling-dependent variation in the histologic staging of dysplasia make clinical risk assessment problematic.
Moreover, poor reproducibility (high inter-observer variation[8], [14]) in histologic assessment often makes clinical risk assessment problematic.
