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Supervised methods for feature selection and classification present several pitfalls (Smialowski et al., 2009), and small datasets make analysis problematic (Martella, 2006).
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Preliminary investigation at the regions of interest shows some spatial patterns that match those for methyphenidate; but the small numbers make formal analysis problematic.
However, the low vigour of some of the lines made analysis of seed weight problematic.
Furthermore, although the dog-wolf issue makes its analysis problematic, the fossil record doesn't support an East Asia origin, others note.
The scarcity of points makes correlation analysis problematic.
Like others, the study is limited by the small patient numbers, making multivariate analysis problematic.
Next-generation sequencing technologies are increasingly being applied in clinical settings, however the data are characterized by a range of platform-specific artifacts making downstream analysis problematic and error- prone.
There were no apparent intertrial patterns in error rates, although this might have been due to a floor effect: Error rates were very low in some combinations of proximity and intertrial condition, reducing variability and making statistical analysis problematic.
The small number of fairs with breeding shows in this study makes analysis of this risk factor problematic; however, the finding is enough to warrant concern given that breeding swine are intended to leave the exhibition and enter a herd for progeny production.
In particular, the restricted range of officially published gender-disaggregated data makes analysis of the current situation of girls and projection of trends very problematic.
These multiple biases are likely to act in different directions and therefore make a censored analysis problematic.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com