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"All of a sudden he's becoming a dominant player, starting to make an escalation we haven't seen.
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"Even a partial de-escalation would make a real difference in the lives of Syrians," she added.
Our results also indicate that the body surface area-based dosing used in pediatric trials can make a difference in dose escalation/de-escalation patterns in the CRM compared to the cases where such variations are not taken into account in the calculations, even leading to different MTDs in some cases.
The risk of escalation may ultimately make a conflict more costly than the initial deterrence was worth.
"The Drug Industry Cashes In" (editorial, Nov. 18) correctly points out that the drug industry's price escalations threaten to make a mockery of its deal with the Senate Finance Committee and the Obama administration.
If a DLT was observed at a lower dose level after escalation, the SMC would make a recommendation on which dose level, if any, to continue to study.
My suggestion that Sandra might like to make a contribution to Geoffrey Wadhurst Coaching Ltd by ironing one, led to a rapid escalation in hostilities.
We also made a game called Escalation!, which is available free for Samsung's old bada phones.
He said: "I don't believe that this second part of the Help to Buy scheme is suddenly going to make that escalation in London prices qualitatively worse.
The commanders couldn't say they didn't have enough time to make the escalation work because they had specifically said, under explicit questioning, that they did.
Beyond the email, the extent to which MoveOn will organize its vast resources to make troops escalation in Afghanistan politically untenable for the president -- and congressional Democrats -- remains to be seen.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com