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Aside from the occasional eclectic discovery, are there areas where amateurs can make a discernible difference to the general body of scientific knowledge?
France gave up without much of a fight with neither Ribéry nor Malouda taking the ball past opponents and another perplexing attacking substitution by Domenech, Mathieu Valbuena for Sidney Govou, failing to make a discernible difference.
And anxieties were running high as everyone waited to see whether Prime Minister Ariel Sharon's order two days ago for greater restraint by the Israeli military was going to make a discernible difference on the ground.
There's Super Smash Bros to come, of course, which may or may not make a discernible difference.
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The addition of an authentic all-rounder has made a discernible difference to the tourists.
The Germany forward made a discernible difference upon his introduction as a half-time substitute in the last-16 victory over Algeria on Monday, injecting power and urgency into a team that had laboured.
My problem with this is that, while I don't think it makes a discernible difference to the finished meringues, it does mean you have to make them before the custard, even though that takes far longer to cool down, and with a dessert this sweet, you really do want it cold, rather than just cool.
Bath's replacements made a discernible difference and t The sustained 14-minute period of pressure close to the Sale line could also have produced a try for Leroy Houston, who believed he had touched down only for the television match official to disagree.
The plan has made a discernible difference to Ridgeview Medical Center, a hospital chain in Minneapolis with 1,400 employees.
He also paid tribute to Washington's financial commitment, saying US efforts to rebuild the country's infrastructure and bring schooling to three million girls had made a discernible difference to the lives of the Afghan people.
In order for health care leaders and professionals to embrace the philosophy of accreditation, they must view it as making a discernible difference in quality and safety as well as a sound business decision.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com