The phrase "make a difference on" is correct and can be used in written English.
For example, you might say, "I'd like to make a difference on environmental issues."
That is how this great university has made a difference on other societal challenges for decades and centuries, and it is how we will make a difference on this one.
"There is such an abundance of buyers, it wouldn't make a difference on the consumption," one told me.
Because each airline has its own seating configurations and policies, a strategy that may work on one airline may not make a difference on another.
"You're the one single individual" who can make a difference on the issue," Mr. DeRose said.
I would rather not have had lane one but it didn't make a difference on the day.
"I felt I wouldn't make a difference on my own, but now I know differently," she said.
Going forward, we can make a difference on several fronts.
The G8 can make a difference on hunger.
So we can make a difference on this.
There religious leaders and laity pledged to make a difference on the climate change challenge.
It's not enough to make a difference on product quality or delivery readiness or production scale.
