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The phrase "make a breakthrough in" is correct and usable in written English
It is typically used to describe achieving significant progress or discovery in a particular field or area of study. Example: "The researchers were able to make a breakthrough in cancer treatment, leading to new therapies."
Exact(45)
"It was baffling that I couldn't make a breakthrough in fiction.
If scientists make a breakthrough in waste disposal, then it may make sense to produce hydrogen from nuclear energy.
After acquiring the computers, Mr. Stillman said, China was able to make a breakthrough in miniaturizing their hydrogen bombs.
Roughly once every two years, trade ministers get together to try to make a breakthrough in the world trade talks.
We recognise that to become the biggest party in the assembly we have to make a breakthrough in the constituencies.
John Major really thought: 'Gosh, here is a chance that we can make a breakthrough in Northern Ireland'".
Similar(15)
He made a breakthrough in 1935.
SpaceX recently made a breakthrough in privatized space flight.
Even the Greens have a shot at making a breakthrough in 2010.
12.23pm: Farage says Ukip has not yet made a breakthrough in local elections.
Finally, after four years of running while dodging Brooklyn traffic, Khannouchi made a breakthrough in 1997.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com