Sentence examples for majority variants from inspiring English sources

One patient had persistent infection with the same pretreatment variant (P31) and two patients (P21, P105) had persistent infection with evidence of a new previously unidentified strain in the posttreatment sample (minority and majority variants, respectively).

The corresponding SA values fall between 0.35 0.58 for DISCRETE, 0.26 0.55 for MERGED, 0.40 0.57 for COMMON, and 0.34 0.56 for MAJORITY variants, and likewise are higher in subsets than in the parent reference set (Table 2).

This was a minority variant in three patients and a majority variant in three patients.

Two patients (P101 and P75) had the same majority variant present pre- and posttreatment.

In the remaining patient, a new majority variant emerged after treatment in addition to a persistent minority variant.

We used these locations to validate predictions arising from our DISCRETE, MERGED, COMMON and MAJORITY variant approaches.

In three of these cases (20%), the new variant represented the majority variant and in three cases (20%), the new variant was a minority strain.

We propose that DAA treatment of mixed infections may be associated with the occurrence of genotype switching, whereby a previously undetected minority variant drug-resistant genotype expands to replace the successfully treated majority variant genotype.

This very high DST may underestimate the potential functional impact of a variant, since the majority of variants showing a very high DS have never been observed in mtDNA genomes from both healthy and diseased individuals.

ClinSeK can be applied to detecting the majority of variants, including SNVs, indels, structural variants and gene fusions from whole genome, whole exome, targeted exome and transcriptome sequencing data.

Although the majority of variants exhibited intermediate complementation relative to the wild type, some variants severely interfered with this complementation.