Though limited efforts have been made to develop picornaviruses as gene therapy or suicide vectors, the vast majority of vector development with picornaviruses has focused on the engineering and use of poliovirus-based vaccine vectors.
These findings are consistent with our observation that in marked contrast to the SFFV and especially the CMV promoters, the A2UCOE is not prone to transcriptional silencing and that the majority of vector integration events are stably productive, giving rise to an efficient rescue of IL2RG deficiency both in vitro and in vivo.
The majority of vector-based siRNAs are generated from short hairpin RNAs (shRNAs).
The majority of vectors for manipulation of Z. tritici have been generated using conventional cloning methods, including the use of restriction enzymes and in vitro ligation protocols (Adachi et al., 2002; Choi and Goodwin, 2011; Marshall et al., 2011; Motteram et al., 2009, 2011; Roohparvar et al., 2007; Zwiers and De Waard, 2001; Zwiers et al., 2007).
However, the majority of secondary vector infections (i.e. vector-host-vector infections) are always in the same patch, regardless of host mixing.
Nevertheless, the majority of adenoviral vector DNA was found in the prostate following the intraprostatic viral injection.
As a result, the majority of adenoviral vectors (AdV) had been derived from these serotypes.
Finally, signals with majority of feature vectors in the abnormal clusters are labeled as the pathological speech and the other signals are classified as normal.
Generally, for most sequences with low and smooth motion, the majority of motion vectors estimated by MCTI are close to the true motion.
While 51 human adenoviral serotypes have been identified to date, the vast majority of adenoviral vectors designed for gene transfer have been generated in the adenovirus serotype 5 (Ad5) backbone.
This is not only because the sequence of every gene is different but also because the majority of existing vectors have been developed independently by different scientists and thus contain different sequences and restriction sites for the insertions of genes.
