The number of polymorphisms per proximal promoter ranged from zero to fourteen, with the majority of transporters (90%) having at least one common (MAF≥5%) polymorphism or multiple singletons in this region.
The lens epithelial cells contain intact organelles and the majority of transporters and metabolic enzymes in the lens [47] [48], while the fiber cells are for the most part devoid of organelles and contain the majority of structural crystallin proteins required for light refraction and lens transparency [49].
However, if one considers mRNA to be representative of function, then the majority of transporters can be expected to have similar activity along the length of the intestine.
The majority of the transporter genes belonged to "Electrochemical potential-driven transporters," "Primary active transporters," and "Channel/pores".
Majority of the transporter genes (782/839) were similar to those cataloged in PHI-base.
The vast majority of these transporter genes (72/74) belong to four solute carrier (SLC) families, including SLC6, SLC22, SLC23 and SLC34 (Table 1), which include transporters of neurotransmitter, organic cation, zwitterion/cation, organic anion, Na+−dependent vitamin C transport and phosphate ion, participating in uptake or excretion of numerous important compounds [ 70- 73].
The pathogenic function of the majority of ABC transporters still awaits elucidation.
Therefore, a common mechanism may be shared by the majority of ABC transporters.
The far majority of the transporters induced in the parental strain lacked a defined function in A. nidulans.
The majority of ABC transporters identified in M. perniciosa belong to the Pleiotropic Drug Resistance (PDR) family and the ABC Conjugate ABCCC) Transporter family.
