Instead, only a small portion of the genome is likely to initiate transcription for a vast majority of transcripts.
For the majority of transcripts regulated at all exposure conditions, fold change values were lowest after 7 days (Figures 3 and 4).
While multiple copies of SMN2 can reduce disease severity, a base change in exon 7 alters splicing fidelity leading to exon 7 exclusion from the majority of transcripts and a non-functional protein.
A single C>T base change in exon 7 of SMN2 results in abnormal splicing with the majority of transcripts missing exon 7 that encodes a crucial oligomerisation domain, and therefore results in a non-functional protein.
Two important questions which need to be addressed in scRNA-seq assays are the minimum number of cells to be sequenced and the sequencing depth at which the majority of transcripts in a cell can be detected.
The majority of transcripts associated with metabolic cycles were dedicated to carbohydrate metabolism, specifically glycolysis.
Global statistical evaluation illustrates that TIF4631 deletion did not affect translational efficiency for the vast majority of transcripts (Fig. S6).
This goal was essentially achieved, since the vast majority of transcripts were quantitatively unaffected in prion-infected vs. mock-infected brains.
Alternatively, it could be distributed over the majority of transcripts.
Upon imposition of stresses, majority of transcripts were down-regulated.
Importantly, the majority of transcripts containing different types of repeats colocalize robustly with MBNL1.
