Sentence examples for majority of somatic from inspiring English sources

The majority of somatic mutations were missense mutations (65%).

The majority of somatic APC mutations in colon cancers result in overexpression of a truncated protein that includes all of the M2-APC region and part of M3-APC (Table 1).

However, the majority of somatic alterations in cancer genomes are a consequence of genomci instability and appear to be passenger or bystander mutations that are unlikely to be involved in oncogenesis [4], [5].

In cancer, the majority of somatic BRAF mutations result in missense substitutions found in, but not limited to, exon 11 (the glycine-rich loop) and exon 15 (the activation segment) in the protein kinase domain [24].

Based on these studies, we can estimate that the majority of somatic mutations in cancer cells are likely to be passenger mutations, whereas a minority are estimated to be driver mutations [5], [7].

In some cases, we obtained ovarian follicles where the majority of somatic cells are mutant for ph (Figure 1H', encircled) and the follicular epithelium seems perfectly normal as evidenced by the regular organization of the nuclei of the mutant cells (Figure 1H,H″, encircled).

Human telomerase, the reverse transcriptase which extends the life span of a cell by adding telomeric repeats to chromosome ends, is expressed in most cancer cells but not in the majority of normal somatic cells.

Due to limited telomerase activity, majority of human somatic cells exhibit progressive shortening of telomeres with each cell division.

Interestingly, the involvement of some unanticipated molecules practically absent from the vast majority of human somatic cells, such as telomerase, was shown recently to be important in mediating the susceptibility to non-targeted intercellular communication effects under stressful conditions.

In addition, we predict Dmef2 binding sites in the −5 to −5.5 kb region.duf −3.8 kb lacZ and duf −5.1 kb lacZ are expressed strongly in majority of the somatic muscle FCs but not in any of the gut muscles.

The majority of the somatic mutations were present in two subpopulations or exclusively detected in only one subpopulation.