Similar to the majority of solid malignant tumours, colorectal carcinoma (CRC) develops metastases that are the major source of morbidity and mortality.
But the vast majority of solid waste – including plastics, polystyrene, polythene and other non-biodegradable materials – is either not collected at all or simply thrown into open municipal dumps and shallow landfills.
The majority of malignant nodules are solid, but the majority of solid nodules are benign.
Cisplatin-based chemotherapeutic regimens are the most frequently used (neo)adjuvant treatments for the majority of solid tumors.
Celecoxib, a selective cyclooxygenase-2 inhibitor, has shown potential anticancerous activity against majority of solid tumors especially on patients with colon cancer.
Fibroblast activation protein-α (FAP), a type 2 dipeptidyl peptidase, is expressed on CAFs in a majority of solid tumors making it an attractive immunotherapeutic target.
Yet the vast majority of solid body electric guitars comes from an industrial mass-production: the manufacturing process is designed for producing guitars that are the most similar possible.
Both transcriptional activators FOXM1B and FOXM1C are upregulated in the majority of solid human cancers [reviewed in 2], [6].
Sub-microscopic alterations of the genome accumulate in cancer progression in an irreversible way and "are compounded by the widespread scrambling of the chromosome structure, and thus the karyotype, found in cells from the great majority of solid tumours" [599].
However, recent accumulating evidence indicates that PI3Kγ functions and is expressed in a much wider range of cell contexts than previously believed; e.g. endothelial cells, cardiomyocytes, cardiofibroblasts, and a vast majority of solid cancer cells [36], [37], [38], [39].
