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The large majority of significantly regulated genes therefore showed very similar expression patterns in both genotypes.
Further, allantoin, N1-methyl-4-pyridone-3-carboxamide, and N-acetylaspartate were inversely correlated with the majority of significantly downregulated genes.
As with the GO term distributions, the majority of significantly enriched KEGG pathways for DEGs between FR and YG were similar to those between FR and MG libraries.
The majority of significantly misregulated genes affected by depletion of Tip60 HAT activity grouped to 17 significantly enriched main and general categories representing general metabolic and cellular processes.
The majority of significantly induced genes in involution were also differentially regulated at earlier stages in the pregnancy cycle.
Consistent with the distributions shown in Figure 3, the majority of significantly affected mRNAs became less stable in OA chondrocytes.
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Unlike the IF males, the majority of the significantly altered pathways were down-regulated in the IF female gonadal tissue.
Overall, the DNL pathway stands out as having a majority of genes significantly altered in their expression due to changing dietary composition.
The majority of the significantly enriched terms were associated with genes that were downregulated following inactivation of p56Lck and thus were located in the lower left quadrant of the plot in Figure 6B (q3 in Table S3).
However, 11168-O grown at conditions mimicking mammalian and avian hosts had, in the majority of cases, significantly reduced Man-binding in comparison to 11168-GS grown under the same conditions.
Interestingly, the 20% CR females showed an opposite response to the 20% CR males, as the majority of their significantly altered pathways were down-regulated compared to the ad libitum control females.
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