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This is a factor that a majority of resistance fighters ignore and is why a majority of novices become de-motivated after a certain period.
For example, we observed erythromycin resistance among isolates of M4, M5, M6, M11, M12, M22, M44, M58, M75, and M94, with the majority of resistance coming from M75.
The majority of resistance studies were conducted prior to 2008.
Based on comparison to the sequenced genomes of Medicago truncatula and Glycine max, these 589 RGHs represent the vast majority of resistance gene homologs in peanut genome.
The vast majority of resistance to rifampicin is caused by mutations located in the 81-bp hotspot region of the rpoB gene [ 9].
The survival rate of heterozygotes is important because they carry the vast majority of resistance alleles in the population and resistance evolves far more rapidly if they possess even a slight advantage over fully susceptible insects.
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Second generation tyrosine kinase inhibitors, such as Dasatinib [13], Nilotinib [14] and Bosutinib [15], [16], are capable of overcoming the majority of resistance-conferring mutations clinically observed, with the exception of the highly IM-resistant gatekeeper mutation T315I.
The majority of NNRTI resistance, 99.1% was caused by a singleton resistance mutation, followed by 68.4% singleton PI resistance mutations and 55.6% singleton NRTI resistance mutations.
In contrast, the majority of mutational resistance mechanisms only result in high-level resistance to one family of antimicrobials.
Isoniazid requires activation in vivo by catalase peroxidase (KatG); it is therefore not surprising that mutations in the katG gene cause the majority of isoniazid resistance (50 90% of isoniazid-resistant strains) [ 103].
One of the 12 members in this cluster, CYP6BQ9, had been demonstrated to be responsible for the majority of deltamethrin resistance observed in QTC279, a deltamethrin-resistant T. castaneum strain [ 30].
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