When SNPs at synonymous sites are categorized into specific base-pair substitutions, the majority of replacements (~60%) are found to be G C to A T transversions (68/112 in the R86 cluster, and 75/126 in the R220 cluster).
Reasons for these missing data are unknown but could be due to the majority of joint replacement patients being (i) older and (ii) having an increased propensity to reside in non-private dwellings such as retirement villages/nursing homes.
Cemented fixation was used in the majority of knee replacements (87 of 117, 74%) whereas 55 of the 74 hip replacements (74%) were cementless.
The majority of their replacements, however, offer pay between $7.51 and $13.52 per hour.
DePuy said that the majority of hip replacements using the ASR devices had been successful.
It is also possible that few centers performed the majority of the replacements, and certain complications could have occurred more often at certain centers.
Structural analysis shows that the majority of these replacements are found in sites that hold non-polar amino acids in the native, non-disease form of the protein.
The majority of these replacements used cementless fixation (either fully cementless (60%, 8,372 of 13,871) or hybrid (15%, 2,064)), or used a resurfacing device (8.4%, 1,159).
It is also noticeable that the majority of the replacements seen in WFDC6 include cysteines from the Kunitz domain, which in EPPIN are engaged in disulfide bonds.
However, it is possible that centers with more experience performed the majority of the replacements in the young patients and thereby more of the patients with FHN, which could have been a possible source of bias.
