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Exact(6)
The majority of radioactivity is found in the plasma fraction indicating high bioavailability of radiotracer [18F]DCFPyL.
Successful RBC labeling with 99mTc was evident due to observed association of the vast majority of radioactivity with the RBC pellet fraction for both naïve and B20-4.1-administered B20-4.1-administered B20-4.1-administered
The polar metabolite fraction, which was also the prominent species in plasma, represented the majority of radioactivity in urine, suggesting that these metabolites are excreted renally.
Moreover, autoradiographic studies, performed on human kidney after in vivo injection of In-peptides, have demonstrated that the majority of radioactivity is deposited within the renal cortex, mainly in the juxtamedullary region.
The majority of radioactivity from plasma samples was associated with the HMW fractions, indicating that the [F]FBEM-ZHER2 342 Affibody was present in the blood at late time points (table insert, F]FBEM-ZHER2 342 Affibody
Since the majority of radioactivity, which contains not only sirolimus metabolites but also sirolimus itself, was found in feces after a single oral dose of C-labeled sirolimus in healthy adults (Rapamune product information; Pfizer/Wyeth-Ayerst), it would be reasonable to assume direct biliary excretion in the PBPK model.
Similar(54)
A majority of internalized radioactivity was lost during the first 3 h of post-incubation.
The majority of the radioactivity of 99mTc(I -L complex was elI -Lated via the liver into the intestine.
The majority of the radioactivity, representing 68Ga-DOTA-exendin-3, was collected in fractions 5 and 6 (2-3 ml).
The fraction containing the majority of the radioactivity was collected (from 3 4 ml), representing 68Ga-colloid, and quality control was performed by ITLC as described above.
With either receptor the majority of the radioactivity was insensitive to TCA treatment, indicating that CXCL12 becomes largely degraded.
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