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After 50 days, the majority of progenitors was undergoing gradual proliferation arrest before eventually undergoing apoptosis.
At P2, the majority of progenitors are typically ready to exit the cell cycle thus upregulating the p27Kip1 as they enter the M phase.
As a consequence of the interkinetic nuclear movement of RG progenitors (Gotz and Huttner, 2005), the majority of progenitors with their nuclei in the intermediate VZ region should be in G1 or in G2.
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The majority of CML progenitors were found to have a higher proliferative capacity compared to normal progenitors, suggesting that most CML progenitors were actively cycling (Eaves et al., 1998).
The majority of cerebellar progenitors at e13.5 derive from the cerebellar ventricular zone, although both cerebellar rhombic lip progenitors and a small number of granule cell progenitors are also present at this time.
By the stage of E17.5 the majority of neuronal progenitors had finished division and differentiated [ 10].
The intensity of labeling for Mash1 strongly decreases in the SVZ, but the vast majority of these progenitors express GAD65.
Such a slow growth is a manifestation of the neutrality of clonal evolution leading to the chance loss of the majority of induced progenitors.
Furthermore, given the absence of Trib2 expression in the majority of myeloid progenitors and mature cells, it is unclear what affect this protein has on normal myelopoiesis.
During their proliferation phase, the majority of these progenitors express Ki-67 (antigen identified by monoclonal antibody Ki-67) and proliferating cell nuclear antigen (PCNA) proteins associated with the cell cycle [ 19].
The majority of SVZ-progenitors mature into GABAergic interneurons in the olfactory bulb [14], [30].
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