Sentence examples for majority of pathway from inspiring English sources

Interestingly, while the female rats on the 20% CR diet showed a similar number of significantly altered pathways (48) the direction of the majority of pathway alterations was opposite to the pathways of the males.

Hence, heme production is mostly controlled by ALAS regulation and not by a majority of pathway members.

Unlike EA methods, it does not explicitly require a majority of pathway genes being activated, but that some covariant expression profiles can be identified.

Both trends were not statistically significant but they were in contrast to the majority of pathway effects reported in the present review.

The results of this study show that for the majority of pathway databases, the overlap between experimentally obtained target genes and targets reported in transcriptional regulatory pathway databases is surprisingly small and often is not statistically significant.

In brief, for the majority of pathway databases used in this study, randomly selected gene sets yield the same number of overlapping genes with gold-standards as the pathway databases.

While the majority of pathways were annotated to fewer than 10% of genera, core pathways were annotated to 34% of genera, multicore pathways to 48%, and supercore pathways to 70% (median values; all enrichments over background had P < 0.001 by Wilcoxon rank-sum tests).

The majority of pathways affected by the high-fat diets exhibit opposite regulation during the early and the late phase of the high-fat feeding time-course.

Thus, the majority of pathways defined by SCNA affected genes in our melanoma samples were recurrent in the three datasets, whereas the individual genes were not.

The majority of pathways were either uniquely populated in the early phase (52 pathways) or expressed during both phases (46 shared pathways) compared to only 22 unique late pathways.

Furthermore the significance of the majority of pathways was not dependent on the established significant (single SNP trend test P<5×10−7) hits, as when the pathway statistic was repeated after excluding significant hits, and known associations, the pathway statistic remained significant for the majority of associated pathways (Table S2).